Fibroblast growth factor 23 plays a protective role against vascular calcification

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MicroRNA-297a regulates vascular calcification by targeting fibroblast growth factor 23

Objective(s): Vascular calcification is one the major characteristics in patients with various types of chronic inflammatory disorders. MiRNAs have been shown to be involved in many normal biological functions as well as diseases; however, their role in vascular calcification has not received much attention. Materials and Methods: In the current study, we built a vascular calcification rat mode...

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microrna-297a regulates vascular calcification by targeting fibroblast growth factor 23

objective(s): vascular calcification is one the major characteristics in patients with various types of chronic inflammatory disorders. mirnas have been shown to be involved in many normal biological functions as well as diseases; however, their role in vascular calcification has not received much attention. materials and methods: in the current study, we built a vascular calcification rat mode...

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The Association between Fibroblast Growth Factor-23 and Vascular Calcification Is Mitigated by Inflammation Markers

BACKGROUND Fibroblast growth factor-23 (FGF-23) has been linked to vascular calcification, ventricular hypertrophy and mortality in chronic kidney disease (CKD), although these links may not be direct and independent. Similar grave outcomes are associated with inflammation and oxidative stress in CKD. Recently, accumulating evidence has linked components of phosphate homeostasis to inflammation...

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Fibroblast Growth Factor 23 and Vascular Calcification: Is It Set in Stone.

health [5] . The volumetric bone mineral density, estimated glomerular filtration rate (eGFR), albuminuria and levels of calcified atherosclerotic plaque (CAP) in coronary, carotid and aortic vascular beds were correlated [5] . After adjusting for covariates, analyses revealed an expected negative correlation with eGFR. However, the core finding observed by the investigators was the association...

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MicroRNA-297a regulates vascular calcification by targeting fibroblast growth factor 23

OBJECTIVES Vascular calcification is one the major characteristics in patients with various types of chronic inflammatory disorders. MiRNAs have been shown to be involved in many normal biological functions as well as diseases; however, their role in vascular calcification has not received much attention. MATERIALS AND METHODS In the current study, we built a vascular calcification rat model ...

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ژورنال

عنوان ژورنال: European Heart Journal

سال: 2013

ISSN: 0195-668X,1522-9645

DOI: 10.1093/eurheartj/eht309.p4164